There’s a magical moment when you pull a bubbling Mac and Cheese Meatloaf Casserole out of the oven, and the cheesy aroma wafts through your kitchen like an irresistible siren song. The golden crust on top crackles as you cut into it, revealing layers of gooey cheese and hearty meat that practically dance with flavor. Quick English Muffin Pizzas Picture this: a cozy family gathering, laughter echoing off the walls as everyone digs in, forks scraping against ceramic plates in a delightful symphony.
Let me tell you, this dish isn’t just food; it’s an experience! It brings back memories of chilly winter nights spent huddled around the table with loved ones, all sharing stories and stealing bites from each other’s plates. Zucchini Ricotta Melts This Mac and Cheese Meatloaf Casserole is perfect for potlucks, lazy Sundays, or whenever you need to impress guests without breaking a sweat. Trust me; your taste buds are in for a treat!
Why You'll Love This Recipe
- This Mac and Cheese Meatloaf Casserole is incredibly easy to prepare, making it perfect for busy weeknights
- The rich flavors combine beautifully to create a comfort dish that everyone will adore
- Its luscious appearance makes it a showstopper at any gathering or family dinner
- With its versatility, you can easily customize ingredients based on personal preferences or dietary needs
I still remember the first time I made this casserole; my friends couldn’t stop raving about it for weeks!

Essential Ingredients
Here’s what you’ll need to make this delicious dish:
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Ground Beef: Use lean ground beef for a healthy twist while still maintaining flavor and moisture.
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Macaroni Pasta: Choose elbow macaroni for a classic texture that perfectly holds onto all that cheesy goodness. For more inspiration, check out this cheesy mushroom chicken lasagna recipe.
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Shredded Cheddar Cheese: Opt for sharp cheddar for robust flavor; feel free to mix in other cheeses for variety.
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Milk: Whole milk adds creaminess; however, feel free to swap with low-fat milk if desired.
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Eggs: Eggs act as a binder, ensuring your casserole holds together beautifully when sliced.
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Breadcrumbs: Use Italian-seasoned breadcrumbs on top for crispy texture and added flavor contrast.
For the seasoning:
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Onion Powder: A must-have for depth; it enhances the overall flavor profile without overpowering.
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Garlic Powder: This aromatic spice adds warmth and richness to every bite.
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Salt and Pepper: Essential seasonings that elevate all the flavors in your casserole.
The full ingredients list, including measurements, is provided in the recipe card directly below.
Let’s Make It Together
Preheat Your Oven: Start by preheating your oven to 350°F (175°C). This ensures even cooking while you prepare everything else.
Cook the Pasta: In a large pot of salted boiling water, cook the macaroni until al dente. Drain and set aside while you work on the meat mixture.
Sauté Ground Beef & Seasonings: In a large skillet over medium heat, brown the ground beef until fully cooked. Add salt, pepper, onion powder, and garlic powder during cooking for maximum flavor.
Combine Ingredients in a Bowl: In a large mixing bowl, combine cooked macaroni with sautéed beef. Stir in milk, eggs, half of your shredded cheese, and mix until everything is well-coated.
Add to Baking Dish & Top It Off: Pour your glorious mixture into a greased baking dish. Sprinkle remaining cheese on top followed by breadcrumbs for an extra crunchy layer.
Bake Until Golden Brown!: Slide the dish into your preheated oven and bake for 30-35 minutes or until golden brown and bubbly. Enjoy watching as it transforms into an irresistible masterpiece!
Once it’s done baking, allow it to cool slightly before serving. Slice up portions that reveal those mouthwatering layers of cheesy goodness—your guests will be lining up for seconds!
This Mac and Cheese Meatloaf Casserole is not just about satisfying hunger; it’s about bringing people together around good food filled with love and laughter. Spicy Italian Crescent Ring Whether you’re hosting friends or enjoying a quiet night in with family, this recipe guarantees smiles all around!
You Must Know
- This delightful Mac and Cheese Meatloaf Casserole combines comfort food favorites into one delicious dish
- The creamy texture and cheesy flavor make it irresistible, while the meatloaf adds a hearty touch
- Perfect for family gatherings or a cozy night in, this dish is sure to please everyone
Perfecting the Cooking Process
Start by preheating your oven to 350°F. Brown the meatloaf mixture on the stovetop first, then combine it with cooked macaroni and cheese for even flavor distribution before baking.

Add Your Touch
Feel free to add veggies like spinach or bell peppers for extra nutrition. You can also swap cheddar for your favorite cheese or use different spices to enhance flavors.
Storing & Reheating
Store leftovers in an airtight container in the fridge for up to three days. Reheat in the microwave or oven until warmed through, ensuring the casserole stays moist.
Chef's Helpful Tips
- For a perfect Mac and Cheese Meatloaf Casserole, remember to season well
- Use high-quality cheeses for that melty goodness
- Don’t skip browning the meat; it adds depth of flavor!
Cooking this casserole always reminds me of cozy nights spent with friends, where laughter and cheesy goodness filled the air. Everyone left with happy bellies and great memories.

FAQ
What type of cheese works best for Mac and Cheese Meatloaf Casserole?
For more inspiration, check out this ground beef casserole recipe.
Cheddar, mozzarella, or a blend of your favorites create a creamy texture. Tomato Mozzarella Gratin.
Can I make this casserole ahead of time?
Absolutely! Prepare it a day ahead and bake just before serving.
How do I know when my casserole is done?
The internal temperature should reach 160°F to ensure it’s fully cooked and safe to eat.

Mac and Cheese Meatloaf Casserole
- Total Time: 50 minutes
- Yield: Serves 8
Description
Mac and Cheese Meatloaf Casserole is a comforting, crowd-pleasing dish that combines the beloved flavors of classic mac and cheese with hearty meatloaf. This easy-to-make casserole features perfectly cooked elbow macaroni enveloped in rich cheddar cheese, layered with savory ground beef, and topped with a crispy breadcrumb crust. Perfect for family dinners or gatherings, this dish promises to warm your heart and satisfy your taste buds!
Ingredients
- 1 lb lean ground beef
- 2 cups elbow macaroni
- 2 cups shredded sharp cheddar cheese
- 1 cup whole milk (or low-fat milk)
- 2 large eggs
- 1 cup Italian-seasoned breadcrumbs
- 1 tsp onion powder
- 1 tsp garlic powder
- Salt and pepper to taste
Instructions
- Preheat your oven to 350°F (175°C).
- Cook the macaroni in salted boiling water until al dente; drain and set aside.
- In a skillet, brown the ground beef over medium heat; season with salt, pepper, onion powder, and garlic powder.
- In a mixing bowl, combine cooked macaroni, sautéed beef, milk, eggs, and half of the cheese; mix well.
- Transfer the mixture to a greased baking dish. Top with remaining cheese and breadcrumbs.
- Bake for 30-35 minutes or until golden brown and bubbly. Allow to cool slightly before serving.
- Prep Time: 15 minutes
- Cook Time: 35 minutes
- Category: Main
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 slice (200g)
- Calories: 450
- Sugar: 4g
- Sodium: 650mg
- Fat: 24g
- Saturated Fat: 10g
- Unsaturated Fat: 12g
- Trans Fat: 0g
- Carbohydrates: 38g
- Fiber: 2g
- Protein: 27g
- Cholesterol: 85mg



